地特胰岛素治疗妊娠糖尿病的疗效

 目的 观察地特胰岛素治疗妊娠糖尿病的临床疗效。方法 选取2016-06至2017-06武警内蒙古总队医院收治的88例妊娠糖尿病患者,随机分为2组,每组44例。对照组皮下注射优泌林N治疗,观察组皮下注射地特胰岛素,比较两组临床相关指标情况。结果 治疗2周后,观察组血糖达标率为79.55%(35/44),高于对照组59.09%(26/44),差异有统计学意义(P<0.05);观察组血糖达标时间(9.33±1.74)d]比对照组短(11.25±2.05)d],且胰岛素用量(16.25±3.24)U]少于对照组(26.35±7.54)U],差异均有统计学意义(P<0.05)。观察组治疗3个月后的FPG、HbA₁c水平均比对照组低,差异均有统计学意义(P<0.05)。观察组妊娠结局明显优于对照组(P<0.05)。结论 妊娠糖尿病应用地特胰岛素治疗后,能有效控制血糖水平,并改善母婴结局,且低血糖发生率低,安全、有效。

Clinical indicators of gestational diabetes treated with insulin detemir

Objective To observe the clinical efficacy and related indicators of insulin detemir in the treatment of gestational diabetes mellitus.Methods The clinical data of 88 patients diagnosed with GDM between June 2016 and June 2017 was selected. According to options of treatment,these patients were divided into two groups, with 44 cases in each. The control group was treated with subcutaneous injection of Humulin N, while the observation group was subcutaneously injected with insulin detemir. The clinically relevant indicators were compared between the two groups.Results After 2 weeks of treatment, the blood glucose index and pregnancy outcome of the observation group were significantly better than those of the control group. The difference was statistically significant(P<0.05).Conclusion For patients with gestational diabetes mellitus, insulin detemir is safe and effective, which can help control their blood glucose levels, improve the maternal and infant outcomes and induce lower incidence of hypoglycemia.