| 加温结合潘生丁增强5－氟脲嘧啶疗效的实验研究 |
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| 引用本文： | 张辅贤,钟竑,朱恩良. 加温结合潘生丁增强5－氟脲嘧啶疗效的实验研究[J]. 上海交通大学学报(医学版), 1994, 0(2) |
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| 作者姓名： | 张辅贤 钟竑 朱恩良 |
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| 作者单位： | 上海第二医科大学附属新华医院成人胸外科 |
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| 摘 要： | 为提高５－氟脲嘧啶疗效，采用ＭＫＮ４５人胃癌细胞株实验研究加温结合潘生丁与５－氟脲嘧啶的协同作用，实验结果表明：单纯加温的抗肿瘤效果不如单独使用５－氟脲嘧啶，潘生丁与５－氟脲嘧啶有协同作用。而加温，潘生丁与５－氟脲嘧啶三者结合的效果最佳。
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| 关 键 词： | 潘生丁，5－氟脲嘧啶，人胃癌细胞株，加温疗法 |
Hyperthermia Combined with DiPyridamole Enhances the Therapeutic Effect of 5 -FU in Vitro |
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| Zhang Fuxian,et al. Hyperthermia Combined with DiPyridamole Enhances the Therapeutic Effect of 5 -FU in Vitro[J]. Journal of Shanghai Jiaotong University:Medical Science, 1994, 0(2) |
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| Authors: | Zhang Fuxian et al |
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| Abstract: | in order to enhance the cytocidal effect of 5-FU, a combined application of hyperthermia and dipyridamole was used additionally to ase the therapeutic effect to the human gastric cancer cell line MKN45 using H-thymidine incorporation test. Results showed that hyperthermia alone is less effective than that of 5-FU alone.Dipyridamole and 5-FU combined produced a synergistic effect the conjoint use of hyperthermia, dipyridamole and 5-FU yielded a maximal therapeutic effect to MKN45 human gastric cancer cell line, |
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| Keywords: | dipyridamole 5-FU human gastric cancer cell line hyperthermia |
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