超早期脑梗死的动脉内接触性溶栓

目的 探讨急性脑梗死的动脉内超早期溶栓治疗。方法 对１９９６年８月～２０００年２月用尿激酶进行超早期（发病至溶栓时间〈６ｈ）动脉内抵触性溶栓治疗１７例急性梗死病例进行回顾性分析。结果 １７例病人血栓或栓子位置分别为：大脑中动脉Ｍ１段１０例，大脑前动脉Ａ段１例，大脑后动脉Ｐ段１例，椎－基底动脉５例。溶栓后血管再通１５例，但１１例有残余狭窄。临床症状完全恢复者１２例，部分恢复者３例，死亡２例，结论 超

Super-early intra-artery thrombolytic therapy for acute brain thrombo-embolism

Objective To explore the early endovascular thrombolytic therapy for acute brain thrombo-embolism. Methods To review the thrombolytic treatment of 17 cases of acute (<6 hours) brain thrombo-embolism with urokinase intraarterially from August 1996 to March 2000. Results Among the 17 patients, thrombi were revealed by angiography with the in middle cerebral artery (M1 segment) in 10 cases, anterior cerebral artery (A1 segment) in 1 case, posterior cerebral artery (P1 segment) in 1 case and vertebral-basilar artery in 5. Recanalization was achieved in 10 patients immediately after thrombolysis, but 11 patients remained with residual stenosis. Clinical symptoms were completely disappeared and restoration was achieved in 12 patients, partical restoration occurred in 3 patients but 2 died. Conclusions Early endovascular thrombolysis with urokinase is one of safely and effective choice to the treatment of acute brain thrombo-embolism.