| 建立溶脲脲原体动物模型的实验研究 |
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| 引用本文： | 路浩,张晓琴,孟林敏,罗予.建立溶脲脲原体动物模型的实验研究[J].河南预防医学杂志,2006,17(3):147-148. |
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| 作者姓名： | 路浩 张晓琴 孟林敏 罗予 |
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| 作者单位： | 1. 河南省医学科学研究所,河南,郑州,450052
2. 河南省医学科学研究所,河南,郑州,450052;郑州大学基础医学院,河南,郑州,450002 |
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| 摘 要： | 目的用溶脲脲原体(ureap lasm a urealyticum,UU)感染雄性大鼠泌尿系统,建立人工溶脲脲原体感染的动物模型。方法采用模拟性交的自然方式使雄性大鼠反复感染UU,16天后处死大鼠,解剖泌尿系统,分别取膀胱、前列腺及尿道中段进行UU培养。结果60%的大鼠尿道中段UU培养阳性,40%的大鼠前列腺UU培养阳性,膀胱UU培养阴性。结论成功建立了溶脲脲原体感染的实验动物模型,有助于研究抗支原体药物的作用及疗效。
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| 关 键 词： | 溶脲脲原体 动物模型 大鼠 |
| 文章编号： | 1006-8414(2006)03-0147-01 |
| 修稿时间： | 2005年12月28 |
Exoerimental studies of animal model of ureaplasma urealyticum infection |
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| LU Hao,ZHANG Xiao-qin,MENG Lin-min,LUO Yu.Exoerimental studies of animal model of ureaplasma urealyticum infection[J].Henan Journal of Preventive Medicine,2006,17(3):147-148. |
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| Authors: | LU Hao ZHANG Xiao-qin MENG Lin-min LUO Yu |
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| Abstract: | Objective:To establish animal model of ureaplasma urealyticm(UU)infection in urinary system of male rats.Methods:The male rats were infected with UU through repeated natural sexual manner.The animals were killed after 16 days and their urinary system was detected.The UU in bladders,prostates and middle urinary tracts was cultured.Results:UU was positive in urinary tracts of 60% rats and inbladders of 40% rats respectively.It was negative in bladder of rats.Conclusion:The laboratorial animal model of ureaplasma urealyticum infection was successful established.It is beneficial to the studies of roles and effects of anti-myocoplasma drugs. |
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| Keywords: | Ureaplasma Urealyticum Animal model Male rat |
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