| 新型肺动脉带瓣管道移植动物实验与血流动力学评价 |
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| 引用本文： | 李子林,刘金成,段维勋,易定华.新型肺动脉带瓣管道移植动物实验与血流动力学评价[J].心脏杂志,2010,22(2):180-182. |
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| 作者姓名： | 李子林 刘金成 段维勋 易定华 |
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| 作者单位： | 1.第四军医大学西京医院心血管外科，陕西 西安 710032；2.解放军第452医院心胸外科，四川 成都 610061 |
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| 基金项目： | 国家863科技计划攻关重大课题(2006AA02A138)资助 |
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| 摘 要： | 目的:对我们与佰仁公司共同研制的肺动脉带瓣管道进行犬移植实验并进行血流动力学评价。方法:肺动脉带瓣管道在体外循环辅助心脏不停跳下对犬行肺动脉瓣置换术,术后持续监测生命体征,术中及术后观察瓣膜血流动力学变化。结果:8条犬6条存活,且存活均超过1个月,存活个体状态良好。死亡的犬中1条由于呼吸机故障,1条可能与瓣膜不匹配有关。手术前后无明显血流动力学变化,手术后右室-肺动脉无明显压差。结论:新型改良肺动脉带瓣管道植入实验犬是适合的。新型肺动脉带瓣管道已显示出优良的血流动力学优势。
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| 关 键 词： | 肺动脉带瓣管道 肺动脉瓣 犬 移植 血流动力学 |
Animal experiments of valve replacement with bioprosthetic pulmonary valve conduit |
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| LI Zi-lin,LIU Jin-cheng,DUAN Wei-xun,YI Ding-hua.Animal experiments of valve replacement with bioprosthetic pulmonary valve conduit[J].Chinese Heart Journal,2010,22(2):180-182. |
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| Authors: | LI Zi-lin LIU Jin-cheng DUAN Wei-xun YI Ding-hua |
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| Institution: | LI Zi-lin1,2,LIU Jin-cheng1,DUAN Wei-xun1,YI Ding-hua1(1.Department of Cardiovascular Surgery,Xijing Hospital,Fourth Military Medical University,Xi\'an,710032,Shaanxi,China,2.Department of Cardiothoracic Surgery,PLA 452 Hospital,Chengdu 610061,Sichuan,China) |
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| Abstract: | AIM: To assess hemodynamic performance of right ventricular outflow tract and pulmonary artery reconstruction(RV-PA) in dogs.METHODS: Eight adult dogs underwent implanted bioprosthetic pulmonary valved conduit in pulmonary position under cardiopulmonary bypass with beating heart.Right ventricular and pulmonary artery pressures were measured directly before and after implantation.RESULTS: Six adult dogs survived in good condition after surgery and survived 1 month after implantation.One dog died from mismatc... |
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| Keywords: | bioprosthetic pulmonary valve conduit dog transplantation hemodynamics |
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