| 三氧化二砷体内化疗对大肠癌细胞凋亡及凋亡调控基因表达的影响 |
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| 引用本文： | 王小兵,杨幼林.三氧化二砷体内化疗对大肠癌细胞凋亡及凋亡调控基因表达的影响[J].黑龙江医学,2011,35(9):645-649. |
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| 作者姓名： | 王小兵 杨幼林 |
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| 作者单位： | 哈尔滨医科大学第一临床医学院消化内科,黑龙江,哈尔滨,150001 |
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| 摘 要： | 目的 通过观察三氧化二砷术前短期体内化疗对大肠癌细胞分子生物学的影响,探讨三氧化二砷抗肿瘤作用的机制,观察短期术前化疗后早期分子生物学指标的变化,评价三氧化二砷在人体内的化疗效果,为其在临床应用于大肠癌的治疗提供依据.方法 取消化内镜检查及活检诊断为大肠腺癌且计划进行手术切除的患者20例,随机分为两组,分别为实验组和空...
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| 关 键 词： | 三氧化二砷 大肠癌 体内化疗 凋亡 |
Influence of Chemotherapy in Vivo with Trioxide Arsenic to Colorectal Cancer on Apoptosis and Apoptosis-related Genes Expression |
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| WANG Xiao-bing,YANG You-lin.Influence of Chemotherapy in Vivo with Trioxide Arsenic to Colorectal Cancer on Apoptosis and Apoptosis-related Genes Expression[J].Heilongjiang Medical Journal,2011,35(9):645-649. |
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| Authors: | WANG Xiao-bing YANG You-lin |
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| Institution: | WANG Xiao-bing,YANG You-lin(Department of Digestive System,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,CHINA) |
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| Abstract: | Objective To observe the influence of chemotherapy in vivo with trioxide arsenic to colorectal cancer on molecular biology,study the chemotherapeutic mechanism of trioxide arsenic,evaluate the chemotherapeutic effects,and search for new clinical methods of trioxide arsenic to treat patients with colorectal cancer.Methods 20 patients,who have been finally diagnosed as colorectal adenocarcinoma through endoscopy and biopsy,were divided into two groups randomly,the test group and the blank control group.10 pat... |
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| Keywords: | Trioxide arsenic Colorectal cancer Chemotherapy in vivo Apoptosis |
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