Systemic lupus erythematosus presenting with mixed‐type fulminant autoimmune hemolytic anemia |
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| Authors: | Yoko Hirano Takaaki Itonaga Hiroki Yasudo Tsuyoshi Isojima Kenichiro Miura Yutaka Harita Masahiro Sekiguchi Motohiro Kato Junko Takita Akira Oka |
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| Affiliation: | Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan |
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| Abstract: | We report the case of a 9‐year‐old girl who presented with mixed‐type fulminant autoimmune hemolytic anemia (AIHA) at the onset of systemic lupus erythematosus (SLE). On admission, laboratory investigations indicated very severe anemia (Hb, 2.7 g/dL) with reticulocytosis and positive direct/indirect Coombs tests. In addition, agglutinative reaction was clinically observed. Based on further examinations, the patient was diagnosed with AIHA complicated with SLE, and mixed‐type AIHA was clinically identified. With oral prednisolone and methylprednisolone pulse therapy, the patient entered remission. |
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| Keywords: | children Coombs test mixed‐type autoimmune hemolytic anemia reticulocytosis systemic lupus erythematosus |
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