上海市奉贤区2008-2010年出生缺陷监测

[目的]了解上海市奉贤区出生缺陷发生情况、分布特征及变化趋势。[方法]采用回顾性分析2008-2010年奉贤区出生缺陷人群监测资料(孕28周至产后42 d)。[结果]监测围产儿总数15 744例,缺陷数277例,出生缺陷率分别为138.94/万,162.28/万,230.66/万,3年发生率有上升趋势。主要缺陷种类顺位依次为先天性心脏病、外耳畸形、脐疝、多指(趾)、并指(趾)、唇腭裂、血管瘤、先天性脑积水、神经管缺陷。[结论]近年来出生缺陷率上升需得到重视,应继续加强监测工作,加强出生缺陷综合防控。

Monitoring analysis on birth defects in Fengxian District of Shanghai from 2008 to 2010

[Objective] To investigate the incidence, distribution and trend of birth defects in Fengxian District of Shanghai. [Methods] The population-based surveillance data of birth defects from 28 gestational weeks to 42 days postpartum was retrospectively analyzed. [Results] A total of 15 744 perineonates were monitored, in which 277 cases of birth defects were detected. From 2008 to 2010, the rate of birth defect was 138.94 per 10 000,162.28 per 10 000 and 230.66 per 10 000, respectively, which indicated a rising trend of incidence. The main types of birth defects in turn were congenital heart disease, deformity of external ear, umbilical hernia, synpolydactyly, syndactyly, chilopalatognathus, hemangioma, hydrocephalus, and neural tube defect. [Conclusion] The rise of birth defects in recent years should be taken seriously. The surveillance and the comprehensive prevention on birth defects should be strengthened.