颈动脉斑块及狭窄与缺血性脑卒中患者认知功能障碍的相关性

目的:初步探讨颈动脉斑块及狭窄与缺血性脑卒中患者认知功能障碍的相关性。方法:回顾性分析44例颈动脉斑块及狭窄合并缺血性脑卒中认知功能障碍患者的资料，采用简易精神状态量表（MMSE）和蒙特利尔认知评估量表（MoCA）评估认知功能，根据颈动脉狭窄程度及部位分为颈动脉轻度、中度及重度狭窄组与左侧、右侧及双侧颈动脉狭窄组，分析各组患者认知功能障碍的差异。结果:颈动脉斑块各组患者的MMSE、MoCA评分差异显著（P<0.05），尤其是重度颈动脉狭窄和左侧颈动脉狭窄患者。结论:颈动脉斑块及狭窄与缺血性脑卒中患者认知功能障碍关系密切。

Correlation of carotid plaque and stenosis to cognitive dysfunction in patients with ischemic stroke

Objective To preliminarily discuss the correlation of carotid plaque and stenosis to cognitive dysfunction in patients with ischemic stroke.Methods The clinical data of 44 patients suffering from carotid plaque and stenosis with cognitive dysfunction after ischemic stroke were analyzed retrospectively.The cognitive function was evaluated by minimental state examination(MMSE)and Montreal cognitive assessment scale(MoCA).After grouping the patients into mild,moderate,severe stenosis groups according to the degree of carotid stenosis,and left,right,bilateral carotid stenosis groups according to the site of carotid stenosis,the differences in cognitive dysfunction among different groups were analyzed.Results The MMSE and MoCA scores in different groups were significantly different(P<0.05),especially in patients with severe carotid stenosis and left carotid stenosis.Conclusion Carotid plaque and stenosis are closely related to cognitive dysfunction in patients with ischemic stroke.