深圳市居民糖尿病危险因素与Ⅱ型糖尿病发病关系的分析

目的 分析深圳地区居民糖尿病危险因子与Ⅱ型糖尿病发病的关系。方法 采用ＷＨＯ诊断标准,随机抽样８１８２人,进行问卷调查,体格检查,血液生化指标测定,用ｌｏｇｉｓｔｉｃ多元回归分析糖尿病危险因素。结果 血清总胆固醇高于正常值范围人群的Ⅱ型糖尿病率为１２．４６％,是正常人群的４．９倍。甘油三酯高于正常值范围人群的Ⅱ型糖尿病患病率为１２．６０％,是正常人群的５．７倍。高密度脂蛋白低于正常值范围人群的Ⅱ型

Risk factors of type 2 diabetes in Shenzhen

OBJECTIVE: The study was designed to investigate the risk factors of Type 2 diabetes in the new city Shenzhen. METHODS: A representative sample of 8,182 adults aged over 20 to 75 years old were randomly selected in the residents of Shenzhen, China in 1997. Type 2 diabetes was diagnosed according to the WHO criteria. Questionnaire survey, anthropometric measurement and blood analysis were carried out, and logistic regression analysis was used to study the risk factors. RESULTS: The results showed that the prevalence of type 2 diabetes in subjects with high total cholesterol were 4.9 times of those with lower TC value. Subjects with high triglyceride had a prevalence 5.7 times of those who had lower TG. Those HDL-ch had a prevalence 68.7% higher than those with normal HDL-ch value; on the other hand, those HDL-ch > 1.91 mmol/L were 44.6% lower in the prevalence than those with normal HDL-ch. The prevalence of type 2 diabetes in subjects with BMI >or= 25 were 2.6 times of those with BMI < 25. Subject with hypertension (>or= 140/90 mm Hg) had a prevalence 3.8 times of those with normal blood pressure. Subjects with family history of type II diabetes had a prevalence 2.0 times of no family history, and women who had delivered babies over 4 kg had a prevalence 1.9 times of those who had babies less than 4 kg. Subjects with waist/hip ratio (WHR) >or= 1.0 had a prevalence 5.1 times of those with WHR < 1.0. The prevalence of type 2 Diabetes was higher with increasing amount of cigarette smoking and the duration (in years) of smoking or increasing drinking (alcohol) and the duration (in years) of drinking. CONCLUSIONS: The blood glucose level was found to be positively correlated with TC or TG, and negatively correlated with HDL-ch. This study demonstrated again that TC, TG, HDL-ch, obesity, hypertension, family history of type 2 diabetes and in women, delivery of babies over 4 kg and age were risk factors of type 2 diabetes.