中西医结合治疗男性少弱精子症的系统评价

目的：评价中西医结合治疗男性少弱精子症的疗效和安全性。方法：检索并选取国内公开发表的关于中西医结合治疗男性少弱精子症的随机对照试验文献，对纳入的文献应用Jadad评分法进行质量评价，采用Reman5．2软件进行Meta分析。结果：共有13项研究符合纳入标准。与单纯西医观察组比较，中西医结合治疗男性少弱精子症的临床疗效比值比OR=3．79，95％可信区间（CI）为（2．51，5．73）。结论：根据目前获得的Meta分析结果显示，中西医结合治疗男性少弱精子症能明显提高临床疗效，增加精子活力、精子密度、精液量及受孕率，同时可以减少精子的畸形率，且无明显的不良反应，安全性好，在临床上值得应用。

Systematic Review of Oligoasthenotspermi Treatment with Integrated Traditional Chinese Medicine and Western Medicine

objective： To assess the Efficacy and safety of combine of Chinese and Western medicine treatment for oligoasthenotspermi. Methods ： we retrieved the domestic publication of integrated traditional chinese medicine and Western medicine treatment for oligoasthenotspermi randomized controlled trials literature, the quality evaluation of included studies use Jadad score method, then use Reman5. 2 software for Meta - analysis. Results： Thirteen studies were included meet the criterion. Compared with control group, the Clinical curative effect of the treatment for oligoasthenotspermi combine of Chinese and Western medicine treatment OR （ odds ratio） 3. 79 ; 95 % confidence interval （CI） （ 2.51,5.73 ）. Conclusion： According to Meta - analysis, integrated traditional chinese medicine and Western medicine treatment for oligoasthenotspermi can obviously improve the clinical curative effect, increase the sperm vitality , density, volume and increase the rate of pregnancy, meanwhile reduce rate of teratosperm, also no obvious adverse reactions, good safety, so this treatment is worth popularizing in clinic.