| 消溃散对溃疡性结肠炎（湿热内蕴型）患者血清IL-8 、IL-10的影响观察 |
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| 引用本文： | 高阳,张长喜,陆琳,毛丽华.消溃散对溃疡性结肠炎（湿热内蕴型）患者血清IL-8 、IL-10的影响观察[J].江西中医学院学报,2014,26(4):31-32. |
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| 作者姓名： | 高阳 张长喜 陆琳 毛丽华 |
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| 作者单位： | 1. 彭泽县中医院 江西彭泽332700
2. 九江市中医院肛肠科 江西九江332000 |
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| 基金项目： | 江西省科技支撑计划项目(项目编号：2013ZBBG70017) |
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| 摘 要： | 目的：观察消溃散对溃疡性结肠炎（UC）患者临床疗效及血清IL-8、IL-10的影响.方法：UC患者60例随机分为观察组和对照组各30例,并设健康对照组.观察组以消渍散治疗;对照组以柳氮磺胺吡啶治疗,疗程均为2个疗程,观察消溃散疗效及其对患者IL-8、IL-10的影响.结果：观察组在改善腹泻、腹痛、粘液脓血便以及结肠镜下粘膜修复方面优于对照组（P＜0.05）.并且可降低血清IL-8、血清IL-10的水平接近健康组,高于对照组（P＜0.05）.结论：消溃散可能通过降低血清IL-8水平和IL-10的水平,从而改善溃疡性结肠炎患者的排便症状.
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| 关 键 词： | 溃疡性结肠炎 血清IL-8 血清IL-10 疗效观察 |
Observation the Effection Xiaokuisan on Serum IL-8, IL-10 in Patients with Ulcerative Colitis |
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| GAO Yang
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ZHANG Chang-xi
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LU Lin
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MAO Li-hua.Observation the Effection Xiaokuisan on Serum IL-8, IL-10 in Patients with Ulcerative Colitis[J].Journal of Jiangxi College of Traditional Chinese Medicine,2014,26(4):31-32. |
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| Authors: | GAO Yang ZHANG Chang-xi LU Lin MAO Li-hua |
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| Institution: | GAO Yang , ZHANG Chang- xi , LU Lin, MAO Li -hua( 1. Pengze Hospital of Traditional Chinese Medicine, Pengze 332700, China; 2. Jiujiang Hospital of Traditional Chinese Medicine, Jiujiang 332000, China.) |
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| Abstract: | Objective To observe Xiaokuisan on ulcerative colitis （UC） clinical therapeutic effect and serum IL -8, IL - 10 patients. Methods： 60 patients with UC were randomly divided into treatment group （30 cases） and control group （30 cases）, and healthy con- trol group. The treatment group therpied by Xiaokuisan; the control group taking sulfasalazine treatment, treatment for 2 courses, ob- servation the curative effect and influence on patients with serum IL - 8, IL - 10 by Xiaokuisan. Results ： The treatment group in im- proving the diarrhea, abdominal pain, mucous stool with pus and blood and repair colon endoscopic mucosa is better than the control group （P 〈0.05）, and can reduce the serum IL- 8, serum IL - l0 level to close to healthy group, higher than that of the control group （P 〈 0.05 ）. Conclusion： Xiaokuisan can reduce the level of serum IL- 8 and IL- 10 levels, improving bowel symptoms in pa- tients with ulcerative colitis. |
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| Keywords: | Ulcerative Colitis Serum IL - 8 Serum IL - 10 Clinical Observation |
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