| 126例丙型肝炎病者临床病毒血清学分析 |
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| 引用本文： | 高志良,姚集鲁,吕凌.126例丙型肝炎病者临床病毒血清学分析[J].中山大学学报(医学科学版),1993(3). |
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| 作者姓名： | 高志良 姚集鲁 吕凌 |
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| 作者单位： | 中山医科大学附属第三医院传染病科
(高志良，姚集鲁)，中山医科大学附属第三医院传染病科(吕凌) |
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| 摘 要： | 分析126例丙型肝炎病者的临床资料,丙型肝炎病毒血清抗体(抗-HCV)滴度及丙型肝炎核酸(HCV-RNA)。发现有明确输血(浆)史者103例,该病史中发现输血后2个月内有肝损者87例占84.4％。抗-HCV检出率为91.3％,其中急性病者检出率82.6％,慢性者95.8％。抗-HCV强阳性者(OD>1.0),HCV-RNA的检出率48.1％,明显高过OD<1.0的低阳性者。抗-HCV阴性者中有18·18％(2/11)检出HCV-RNA。另外,HCV-RNA的检出与谷-丙转氨酶(ALT)水平有一定关系,有肝损者比ALT正常者HCV-RNA检出率明显高。提示HCV-RNA的检出与活动性肝病有关系。
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| 关 键 词： | 丙型肝炎病毒 抗体 核糖核酸 |
SEROLOGICAL ANALYSES OF 126 PATIENTS WITH HEPATITIS C |
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| Gao Zhiliang Yao Jilu Lu Ling.SEROLOGICAL ANALYSES OF 126 PATIENTS WITH HEPATITIS C[J].Journal of Sun Yatsen University(Medical Sciences),1993(3). |
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| Authors: | Gao Zhiliang Yao Jilu Lu Ling |
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| Abstract: | One-hundred and twenty-six hepatitis C patients were investigated. Of them, 103 cases had blood product transfusion history, 2 months after transfusion liver damage developed in 84.4% of 126 patients, 91.3% were anti-HCV positive. Anti-HCV posit-ivily was found in 82.6% of acute infections and in 95.8% of chronic cases. 18.2% of anti-HCV negative cases were found to be HCV RNA positive. In addition, a high detection rate of HCV RNA in ALT abnormal cases was observed. It suggested that HCV RNA could be related to active liver damage. |
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| Keywords: | hepatitis C virus anti-body RNA |
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