红外热成像在女童性早熟中的诊断价值

<正>性早熟是指男童在9周岁之前、女童在8周岁之前出现第二性征,或者女童在10周岁前出现月经初潮^[1-2]。近年来其发病率呈上升趋势,其中女童明显高于男童^[3-4]。性早熟作为儿科第二大常见内分泌系统疾病,其对儿童身心发育均有不良影响^[5-7]。

Study on the clinical application value of Thermal Texture Maps in the diagnosis of precocious puberty in girls

Abstract: Objective: To detect the distribution pattern of body surface heat values in girls with precocious puberty and the subtypes (central/peripheral) by Thermal Texture Maps (TTM) and to evaluate its predictive efficacy for early diagnosis of precocious puberty in children. Methods: Thirty girls with central and peripheral precocious puberty and 60 healthy girl volunteers were recruited to compare and analyze the differences in their infrared thermographic characteristics. The diagnostic criteria of TTM for precocious puberty in girls were investigated, and its diagnostic efficacy was evaluated. Results: The body surface heat values in the governor meridian region and knee region of girls with precocious puberty were higher than those of healthy girls, and the deviations of body surface heat values in the lower abdominal region and bilateral breast region were greater than those of healthy girls, and the differences were statistically significant (P<0.05). Typical infrared thermograms of girls with precocious puberty showed continuous deep red (indicating a higher body surface temperature) in the governor meridian area, symmetrically distributed light red areas in the bilateral calves area centered on Zusanli Point (indicating a higher body surface temperature), and blue-green area or light red area in the lower abdomen and bilateral breasts (indicating a higher or lower body surface temperature).The body surface heat values in the bladder uterine region, bilateral adnexal region, and lower abdominal region were higher in girls with central precocious puberty than in girls with peripheral precocious puberty (P<0.05). The accuracy rate of TTM in diagnosing girls with precocious puberty was 82.5%, and the accuracy rate of diagnosing girls with central and peripheral precocious puberty was 71.7%. Conclusion: TTM technique can objectively reflect the difference of abnormal body surface caloric values and their distribution pattern in girls with precocious puberty, and it has good diagnostic efficacy for precocious puberty and its subtypes.