应用CT分析大脑中动脉钙化与脑梗死的关系

目的分析大脑中动脉水平段（M1段）钙化与相应供血区脑梗死的关系.方法经CT确诊的大脑中动脉M1段钙化患者121例（151支）,分析钙化的形态学特点、部位以及与血管的关系;用Cascoring自动分析软件计算钙化积分.对大脑中动脉钙化组与无钙化组脑梗死发病率及大脑中动脉钙化组中有或无梗死灶与钙化积分诸指标的关系进行分析.结果小结节状钙化121支,大结节状钙化18支,条状钙化12支.76支钙化位于大脑中动脉M1近段,55支位于大脑中动脉M1中段;20支钙化位于M1远段.钙化斑块与血管的关系,向心性43支,偏心性108支.大脑中动脉钙化组脑梗死发病率（51.7%）高于无钙化组（27.5%）,差异有显著意义（P＜0.01）;有梗死灶组钙化体积、钙化质量及积分大于无梗死灶组,差异亦有显著意义（P＜0.01）.结论CT容积扫描能显示大脑中动脉细小钙化,并能对钙化分型,确定钙化的部位.大脑中动脉钙化与否及钙化积分诸指标的大小与脑梗死的发生与否密切相关,钙化组比无钙化组更易发生脑梗死;有梗死灶组的钙化程度比无梗死灶组更严重.

The relationship between middle cerebral artery calcification and cerebral infarction: a contrast analysis by CT scanning

Objective To analyze the relationship between the calcification characteristics of middle cerebral artery(MCA) M1 segment and the cerebral infarction in its supplying areas.Methods A total of 121 patients(151 arteries) with MCA M1 segment calcification in our hospital were diagnosed by CT from July to August 2005.The characteristics pattern of calcification,the location and its relation with the vessels were analyzed.Calcification scores were calculated using Cascoring automatic analysis software.Whether there were infarct foci and the numbers of infarct focus in the supplying areas of the bilateral MCA were determined.The incidence of cerebral infarction in MCA calcification group and MCA non-calcification group,as well as the relationship between with or without infarct foci in the MCA calcification group and the various calcification score indexes were analyzed statistically.Results One hundred twenty-one arteries had small nodular calcifications,18 had large nodular calcifications,and 12 had linear calcifications.The calcification of 76 arteries located in the proximal M1 segment,55 in the middle M1 segment,and 20 in the distal M1 segment.The relationship between calcific plaques and arteries: centripetal 43 arteries,eccentric 108 arteries.The incidence of cerebral infarction(51.7%) in the MCA calcification group was higher than that of the non-calcification group(27.5%),and there was statistical significance between the 2 groups(P<0.01).The calcific volume,mass and score in the infarcted group were greater than those in the non-infarcted group(P<0.01),and there was also statistical significance between the 2 groups(P<0.01).Conclusion CT volume scan may show tiny calcifications in MCA,and may classify and determine the location of calcifications.Whether MCA calcification or not and calcification scores in various indexes are closely associated with the development of cerebral infarction.The calcification group is more likely to develop cerebral infarction than the non-calcification group.The severity of calcification in the infarcted group is more serious than that of the non-infarcted group.