| 四氢叶酸模型的合成及水解反应对四氢叶酸的模拟 |
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| 引用本文： | 陈建新,夏炽中,杜红旺. 四氢叶酸模型的合成及水解反应对四氢叶酸的模拟[J]. 大同医学专科学校学报, 1997, 0(2) |
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| 作者姓名： | 陈建新 夏炽中 杜红旺 |
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| 作者单位： | 大同医专生化研究室，山西大学化学系，山西大学化学系 037008 |
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| 摘 要： | 本文合成了四氢叶酸模型化合物碘化1,2—二甲基—3—对甲氧苯磺酰基咪唑啉,模拟四氢叶酸甲酸氧化态的形式,进行了水解反应,发现此模型很好地模拟了四氢叶酸的行为,通过水解形成两种互变异构体化合物。
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| 关 键 词： | 四氢叶酸模型 合成 水解 |
Synthesis of tetrahydrofolate models hydrolysis mimicking tetrahydrofolate |
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| Chen Jianxin,Xia Chizhong,Du Hongwang. Synthesis of tetrahydrofolate models hydrolysis mimicking tetrahydrofolate[J]. Journal of Datong Medical College, 1997, 0(2) |
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| Authors: | Chen Jianxin Xia Chizhong Du Hongwang |
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| Affiliation: | Department of Chemystry of Datong Medical College |
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| Abstract: | This Paper has synthesized 1,2 -dimethyl - 3-(P - methoxybenzenesulfonyl) imidaZOlinium iodide,which serves as tetrahydrpfolate models in terms of mimicking tetrahy-drofolate at the oxidation level of formate,It has been found that the model had mimicked the hydrolyze property of tetrahydrofolate and formed two-isomeric compounds. |
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| Keywords: | Tetrahydrofolate Models Synthesis Hydrolysis |
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