温州地区艾滋病感染者和病人合并感染乙肝、丙肝、梅毒等疾病的研究

目的:研究艾滋病感染者和病人(HIV/AIDS)合并感染乙型病毒性肝炎(HBV)、丙型病毒性肝炎(HCV)、梅毒(TP)的流行现状及其特点,为HIV/AIDS的防控和治疗提供科学依据。方法:选取2008年-2010年期间在温州实验室确认阳性的艾滋病感染者和病人的标本共678例,采用ELISA法,分别对标本进行乙肝表面抗原、丙肝抗体、梅毒抗体项目检测。结果:其中,合并感染乙肝的有102例(15.04%),感染丙肝84例(12.38%),感染梅毒145例(21.38%);同时感染乙肝、丙肝的有13例(1.91%),感染乙肝、梅毒有31例(4.57%),感染丙肝、梅毒的有13例(1.91%),同时感染乙肝、丙肝、梅毒的2例(0.29%)。结论:1、HIV感染者中HBV感染率略高于普通人群;HIV与HCV合并感染率显著高于普通人群,但低于国内外报道的HIV/HCV的30%以上;HIV与TP合并感染的比例显著高于普通人群以及其他地区艾滋病患者。2、合并感染的总体趋势有所控制。

Research on the situation of HIV/AIDS coinfected with HBV,HCV,TP and other diseases in Wenzhou area

Objective: To provide important scientific basis for control and treatment of HIV/AIDS through the study on the epidemic characteristics of HIV-infected people and patients(HIV/AIDS) co-infected with hepatitis B(HBV),hepatitis C(HCV) and syphilis(TP).Methods: A total of 678 cases laboratory-confirmed HIV-positive specimens in 2008-2010 in Wenzhou were selected to detect HBsAg,HCV and syphilis antibody with ELISA method.Results: A total of 678 cases of HIV/AIDS specimens were found that hepatitis B infection was 102 cases(15.04%),hepatitis C infection was 84 cases(12.38%),syphilis infection was 145 cases(21.38%);while coinfection with hepatitis B and hepatitis C was 13 cases(1.91%),coinfection with hepatitis B and syphilis was 31 cases(4.57%),coinfection with hepatitis C and syphilis was 13 cases(1.91%),and coinfection with hepatitis B,hepatitis C and syphilis was 2 cases(0.29%).Conclusion: 1.The rate of HIV and HBV co-infection was slightly higher than the general population;the rate of HIV and HCV co-infection was significantly higher than the general population,but lower than that in the domestic and international report;while HIV and TP co-infection rate was significantly higher than that of the general population and AIDS patients in other areas.2.The overall trend of co-infection has been controlled.