家族性渗出性玻璃体视网膜病变治疗观察

目的 观察家族性渗出性玻璃体视网膜病变（FEVR）激光光凝和玻璃体视网膜手术治疗的疗效。 方法 回顾性分析1997年1月至2005年8月 期间临床诊断的FEVR患者17例32只眼的临床资料。根据患眼病变轻重程度不同选择治疗方法 ,其中7只眼(1期2只眼、2A期1只眼和2B期4只眼)采用周边视网膜激光光凝治疗，治疗后随访 6～108个月,平均随访时间30.29个月。13只眼(3B期2只眼、4A期1只眼、4B期6只眼和5A期4 只眼)采用玻璃体视网膜手术治疗，手术后随访3～72个月，平均随访时间23.19个月；另外 12只眼因病变太严重、年龄及家属选择等原因未接受治疗。 结果 接受激光光凝治疗的7只眼随访期间病情稳定,视力保持不变。接受玻璃体视网膜手术治疗的13只眼,除1只眼外12只眼黄斑区均达到解剖复位。9只眼手术后视力提高,3只眼手术后视力保持不变,1只眼视力检查不合作。 结论 激光光凝能控制FEVR病情发展；玻璃体视网膜手术有利于促进FEVR患者视网膜复位和提高视力。两种治疗方法是治疗FEVR的有效手段。 （中华眼底病杂志，2006，22：302-304）

Treatment for familial exudative vitreoretinopathy

Objective To observe the surgical effects of photocoagulation and vitrectomy on familial exudative vitreoretinopathy (FEVR). Methods The data from 32 eyes of 17 patients with FEVR diagnosed in our department from January 1997 to August 2005 were analyzed retrospectively. The methods of treatment had been chosen according to the disease extents. Seven eyes ( stage 1 in 2 eyes, 2A in 1 eyes, and 2B in 4 eyes) had undergone peripheral photocoagulation with the follow-up period of 6-108 months (the average was 20.29 months); vitrectomy had been performed on 13 eyes(stage 3B in 2 eyes,4A in 1 eyes, 4B in 6 eyes, and 5A in 4 eyes) with the follow-up period of 3-108 months ( the average was 20.65 months); 12 eyes had received none of the treatments due to the serious extents, age, and the selection of the patients′ relations. Results In 7 eyes treated with peripheral photocoagulation, the disease was stable and visual acuity remained unchanged during the follow-up period . In 13 eyes undergone vitrectomy, reattached retina was found in 12; visual acuity improved in 9, kept still in 3, and was unknown in 1 because of the patient ′s noncooperation. Conclusion Photocoagulation may prevent the development of FEVR, and vitrectomy can promote the reattachment of retina and improvement of the visual acuity in patients with FEVR. These two treatments are effective on FEVR.  （Chin J Ocul Fundus Dis，2006，22：302-304）