冠心病与颈动脉粥样硬化超声标识的相关性研究

目的探讨颈动脉粥样硬化与冠状动脉粥样硬化的关系。方法对冠状动脉造影证实为冠心病54例(冠心病组)和非冠心病组(对照组)41例,行双侧颈动脉超声检查,测定血管后壁内膜-中膜厚度(IMT),记录斑块数目,并半定量估计其严重程度。据冠状动脉造影结果分为正常组和冠心病组。冠心病组按血管狭窄累及主要病变血管支数分为:单支病变、双支病变、多支病变。结果随冠状动脉病变程度的增加,颈动脉IMT值增加,冠心病组与正常组比较差异有统计学意义(P<0.05);颈动脉斑块分级与冠状动脉病变血管支数分级间密切相关(P<0.05)。结论颈动脉粥样硬化超声标识可间接预示冠心病的严重程度。

Association between coronary artery disease and ultrasonic signals of carotid atherosclerosis

Objectives To observe the relationship between carotid atherosclerosis and coronary artery atherosclerosis.Methods The intima-media thickness(IMT) were measured in 54 patients with coronary artery disease(CAD)and in 41 patients without CHD diagnosed by coronary arteriography(CAG).The numbers of plaque were recorded and the grades were semi-quantified.These patients were divided into normal group and CAD group.The extent of CAD was coded as 1,2 branches or more according to the number of major coronary vessels with luminal stenosis.Results The IMT progressively increased with the extent of CAD,the IMT of CAD group was obviously higher than that of normal group(P<0.05);there was significant correlation between the plaque grades and the extent of CAD(P<0.05).Conclusion Ultrasonic signals of carotid arteriosclerosis have great value in predicting the extent of CAD.