| 绞股蓝总皂甙减轻小鼠血吸虫性肝纤维化的实验观察 |
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| 引用本文： | 廖力,张愉快,王可耕.绞股蓝总皂甙减轻小鼠血吸虫性肝纤维化的实验观察[J].南华大学学报(医学版),1998(2). |
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| 作者姓名： | 廖力 张愉快 王可耕 |
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| 作者单位： | 衡阳医学院寄生虫学教研室 |
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| 摘 要： | 本实验采用绞股蓝总皂甙（ＧＰｓ）治疗小鼠血吸虫病，观察其对血吸虫性肝纤维化的影响。结果表明：ＧＰｓ治疗组肝虫卵肉芽肿反应增长比和肝纤维化程度均明显小于感染对照组（Ｐ＜０．０５）。提示ＧＰｓ具有减轻血吸虫性肝纤维化的作用。也提示自由基在血吸虫虫卵肉芽肿形成和发展中起了重要作用
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| 关 键 词： | 血吸虫病 肝纤维化 绞股蓝总皂甙 |
Studies on Experiment of Gypenosides Decreasing Fiberosis in the Liver Tissue of Schistosoma Japonicum Infected Mice |
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| Liao Li,Zhang Yukuai,Wang Kegeng.Studies on Experiment of Gypenosides Decreasing Fiberosis in the Liver Tissue of Schistosoma Japonicum Infected Mice[J].Journal of Nanhua University(Medical Edition),1998(2). |
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| Authors: | Liao Li Zhang Yukuai Wang Kegeng |
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| Abstract: | The article reports the inhibitive effect of gypenosides(GPs) on liver fiberosis of Schistosoma japonicum infected mice.In Gps treated group,the granuloma reaction and the level of liver fiberosis were less than that of control group(P<0.05).The results suggested:(1)Gps could decrease liver fiberosis of schistosoma japonicum infected mice;(2)Free radicals played an important role in granulom formation and improvement. |
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| Keywords: | schistosoma japonicum liver fiberosis gypenosides |
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