在导航引导下经鼻蝶切除垂体腺瘤治疗效果的研究

目的探讨在导航引导下经鼻蝶切除垂体腺瘤的治疗效果。方法回顾2004-2005 年导航引导与非导航引导下经鼻蝶切除垂体腺瘤患者57例,对所有病例分别统计术前年龄、肿瘤大小、手术麻醉时间、切除肿瘤时手术时间、术后住院天数、术后并发症,术后3个月复查MRI提示肿瘤全切程度,结果用SPSS 11．0软件进行统计,分析两组之间结果的差异。结果导航组与非导航组中患者年龄、肿瘤大小、麻醉时间、手术后住院天数、术后并发症方面无显著性差异,而手术时间及术后3 个月复查MRI提示肿瘤全切率有显著性差异。结论在导航引导下经鼻蝶切除垂体腺瘤提高了垂体腺瘤患者肿瘤的全切率,缩短了手术切除肿瘤的时间。

The effect of neuronavigator-guided microsurgery on resection of pituitary adenomas via transsphenoidal approach

Objective To study the effects of neuronavigator-guided microsurgery on resection of pituitary adenomas via transsphenoidal approach. Methods 57 cases undergoing neuronavigator-guided and non-neuronavigator-guided resection of pituitary adenomas via transsphenoidal approach were investigated in respect to age, tumor, anesthetic time, time for removing tumor, postoperative days for hospitalization, postoperative complications, and the extent of tumor resection by MRI 3 months after surgery, all of which were analyzed between neuronavigator guided group and non-neuronavigator guided group with SPSS 11.0. Results There was no significant difference between neuronavigator guided group and non-neuronavigator guided group in age, tumor, anesthetic time and postoperative inpatient days, except in time of removing tumor and extent of tumor resection by MRI 3 months after surgery. Conclusion Resection of pituitary adenomas via transsphenoidal approach under neuronavigator guidance not only improves the ratio of total removal, but shortens the time of removing tumor as well.