| 体外循环冠状动脉旁路移植术围术期血浆血管加压素变化及对血液动力学的影响 |
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| 引用本文： | 潘晓静,程卫平. 体外循环冠状动脉旁路移植术围术期血浆血管加压素变化及对血液动力学的影响[J]. 中国体外循环杂志, 2010, 8(1): 41-44 |
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| 作者姓名： | 潘晓静 程卫平 |
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| 作者单位： | 1. 北京协和医学院中国医学科学院阜外心血管病医院麻醉科,北京,100037
2. 首都医科大学附属北京安贞医院麻醉科,北京,100037 |
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| 摘 要： | 目的探讨体外循环(ECC)冠状动脉旁路移植术(CABG)围术期血浆血管加压素(AVP)变化及对血液动力学和术后转归的影响。方法随机选择择期ECC下行CABG患者40例。分别在麻醉诱导前、切皮前、ECC开始、复温、ECC结束、手术结束、术后24h采集动脉血液样本测定血浆AVP浓度,并在切皮前和ECC结束后10min监测血液动力学指标。详细记录患者围术期临床资料。根据血浆AVP浓度的不同水平通过聚类分析将40例患者分为高值组(n=22)和低值组(n=18)。结果围术期血浆AVP浓度呈现完全不同的变化趋势。与高值组相比,低值组患者ECC后高排低阻的发生率较高(P0.01);ECC后平均动脉压较低(P0.01);ECC时间(P0.01)、术后带管时间(P0.01)、ICU停留时间(P0.05)和术后住院时间(P0.05)较长;血管收缩药的使用人数较多(P0.01)。结论ECC下CABG围术期血浆AVP浓度呈现两种完全不同的变化,低值组患者的血液动力学及术后转归较差。
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| 关 键 词： | 血管加压素 冠状动脉旁路移植术 体外循环 血液动力学 |
Perioperative plasma levels and hemodynamic effects of arginine vasopressin in patients undergoing on-pump coronary artery bypass grafting |
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| Pan Xiao-jing,Cheng Wei-ping. Perioperative plasma levels and hemodynamic effects of arginine vasopressin in patients undergoing on-pump coronary artery bypass grafting[J]. Chinese Journal of Extracorporeal Circulation, 2010, 8(1): 41-44 |
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| Authors: | Pan Xiao-jing Cheng Wei-ping |
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| Affiliation: | Pan Xiao-jing,Cheng Wei-ping Department of Anesthesiology,Fu Wai Hospital,CAMS , PUMC,Beijing 100037,China |
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| Abstract: | OBJECTIVE To investigate the change of perioperative plasma arginine vasopressin (AVP)concentration during on-pump coronary artery bypass grafting (CABG),and its effects on hemodynamics and postoperative outcomes. METHODS Forty patients undegoing elective on-pump CABG were randomly enrolled in this study. Blood samples were collected to determine the plasma AVP concentration at the following points:before induction of anesthesia,before skin incision,onset of extracorporeal circulation (ECC),rewarming period... |
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| Keywords: | Arginine vasopressin Coronary artery bypass grafting Extracorporeal circulation Hemodynamics |
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