| 注射用盐酸雷莫司琼与4种输液配伍的稳定性考察 |
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| 引用本文： | 宋飞.注射用盐酸雷莫司琼与4种输液配伍的稳定性考察[J].安徽医药,2008,12(1):15-16. |
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| 作者姓名： | 宋飞 |
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| 作者单位： | 广西医科大学第四附属医院,广西,柳州,545005 |
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| 摘 要： | 目的考察注射用盐酸雷莫司琼在5％葡萄糖注射液等4种输液中的稳定性。方法在25℃，将注射用盐酸雷莫司琼加入到4种输液中，模拟临床用药浓度，用高效液相色谱法测定配伍后不同时间配伍液的含量，同时检查配伍液的pH值和外观变化。结果注射用盐酸雷莫司琼与4种输液配伍后在25℃放置10h其外观、pH值和含量基本不变。结论注射用盐酸雷莫司琼与4种输液配伍，在10h内基本稳定。
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| 关 键 词： | 雷莫司琼 输液 稳定性 |
| 收稿时间： | 2007-08-27 |
| 修稿时间： | 2007年8月27日 |
Compatibility of ramosetron hydrochloride for injection with four kinds of injections |
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| SONG Fei.Compatibility of ramosetron hydrochloride for injection with four kinds of injections[J].Anhui Medical and Pharmaceutical Journal,2008,12(1):15-16. |
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| Authors: | SONG Fei |
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| Institution: | SONG Fei ( The No. 4 Affiliated Hospital of Guangxi Medical University,Liuzhou 545005, China) |
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| Abstract: | Aim To investigate the compatibility of ramosetron hydrochloride for injection with four kinds of injection solutions. Methods Changes of content, pH and appearance of ramosetron hydrochloride for injection within 10 hours under 25℃ after combination with respective injections as simulated clinic therapy concentration were measured and observed. Results Significant changes of appearance, pH and content had not been observed within 10 hours under 25℃, when ramosetron hydrochloride for injection was combined with four kinds of injection solutions respectively. Conclusion It is stable within 10 hours under 25℃ after ramosetron hydrochloride for injection was combined with four kinds of injection solutions. |
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| Keywords: | amosetron injection stability |
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