脉压差对高血压病患者颈动脉粥样硬化的作用

目的 :高血压病是冠状动脉粥样硬化的危险因素 ,人们普遍关心收缩压与舒张压和动脉粥样硬化与冠心病的关系 ,而对于脉压尚未进行广泛的研究。方法 :本文通过多普勒超声检查高血压病患者颈动脉粥样硬化的方法 ,观察了 64例高血压病患者脉压差与颈动脉粥样硬化斑块的发生率及内中膜厚度的相互关系。结果 :脉压差高的患者其颈动脉粥样硬化斑块的发生率及内中膜厚度也高 (P <0 0 5 ,P <0 0 1)。结论 :脉压差与颈动脉粥样硬化斑块和内中膜厚度相关 ,脉压差可能参与动脉粥样硬化的形成和发展。

Effects of increased pulse pressure on carotid arterioles atherosclerosis of hypertensive patients

Objective:Hypertension is a risk factor of coronary artery atherosclerosis.The relation of the systolic pressure and diastolic pressure and atherosclerotic heart disease has been concerned,but the effect of the correlation of the pulse pressure to atherosclerosis is not very clear.Method:By the Doppler Ultra Sound echocardiography,we examined the rate of carotid atherosclerotic plaque and the carotid intimal\|medial thickness of 64 hypertensive patients and observed the relationship of pulse pressure and the rate of carotid atherosclerotic plaque and carotid intimal\|medial thickness.Result:The rate of carotid atherosclerotic plaque and the carotid intimal\|medial thickness of the hypertensive patients with high pulse pressure were significantly increased( P<0\^05,P<0\^01) .Conclusion:The pulse pressure is related to carotid atherosclerotic plaque and the carotid intimal\|medial thickness.The pulse pressure may take part in the forming and developing of atherosclerosis.