| 增强剂量CHOP方案治疗非霍奇金淋巴瘤51例 |
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| 引用本文： | 黄强,孙酬经,汪涟明,钱美华,蓝建平,杨天新,王文松.增强剂量CHOP方案治疗非霍奇金淋巴瘤51例[J].肿瘤学杂志,1998(4). |
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| 作者姓名： | 黄强 孙酬经 汪涟明 钱美华 蓝建平 杨天新 王文松 |
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| 作者单位： | 浙江省人民医院!杭州，310014，浙江省人民医院!杭州，310014，浙江省人民医院!杭州，310014，浙江省人民医院!杭州，310014，浙江省人民医院!杭州，310014，浙江省人民医院!杭州，310014，浙江省人民医院!杭州，310014 |
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| 摘 要： | 〔目的〕探讨增强剂量CHOP方案治疗非霍奇金淋巴瘤的临床完全缓解率和3年生存率及骨髓抑制等情况。（方法）对51例非霍奇金淋巴瘤患者进行增强剂量CHOP方案治疗及良好的支持治疗并长期、定期治疗及随访。（结果）全组完全缓解率为784％；3年生存率为779％。（结论）增强剂量CHOP方案与传统CHOP方案相比在完全缓解率和3年生存率上有明显提高，而其骨髓抑制等毒副反应未见明显增加。
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| 关 键 词： | 非霍奇金氏淋巴瘤 毒副反应 药物疗法 环磷酰胺 长春新碱 |
Treatment of Non-Hodgkin's Lymphoma with Reinforced CHOP Regimen (51 Cases Report) |
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| Huang Qiang, Sun Choujin, Wang Lianhang,et al..Treatment of Non-Hodgkin's Lymphoma with Reinforced CHOP Regimen (51 Cases Report)[J].Journal of Oncology,1998(4). |
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| Authors: | Huang Qiang Sun Choujin Wang Lianhang |
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| Institution: | Huang Qiang, Sun Choujin, Wang Lianhang, et al. |
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| Abstract: | Purpose] To study the effect of reinforced CHOP regimen in treating Non-Hodgkin's Lymphoma(NHL) in termsof clinical complete remssion(CR) rate, 3-year survival rate, and bone marrow inhibition. (Method] We used rein forced CHOPregimen to treat 51 NHL patients, along with supporting therapy, followed by regular, long-term treatment and follow-up. Re-sult]The CR rate was 78. 4%, the 3-year survival rate was 77. 9%. Conclusion] Reinforced CHOP reg imen has s igni ficant im-provement over traditional CHOP regimen in treating NHL in terms of CR rate and 3-year survival rate, and little increase in side-effect including bone marrow inhibition. |
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| Keywords: | Non-Hodgkin's lymphoma Adverse effect Drug therapy Cyclophosphandde Vincristine |
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