https://orcid.org/0000-0003-1102-1600;2. European Centre for Environment and Human Health, College of Medicine and Health, University of Exeter, Knowledge Spa, Royal Cornwall Hospital, Truro, Cornwall, UK;3. Miriam C. Noonan, European Centre for Environment and Human Health, Knowledge Spa, Royal Cornwall Hospital, University of Exeter Medical College of Medicine and Health, Truro, Cornwall, UK.;4. Primary Care Research Group, College of Medicine and Health, University of Exeter, Exeter, UK;5. Institute of Health Research, College of Medicine and Health, University of Exeter, Exeter, UK;6. Royal Cornwall Hospitals NHS Trust, Truro, UK;7. Institute of Health and Well Being, University of Glasgow, Glasgow, UK