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正交试验优选延胡索提取工艺
引用本文:陈中兰,李锐.正交试验优选延胡索提取工艺[J].中国中医药咨讯,2011,3(16):266-267.
作者姓名:陈中兰  李锐
作者单位:钟祥市人民医院药剂科,湖北,钟祥,431900
摘    要:目的:优选延胡索最佳提取工艺。方法:采用正交试验法,以延胡索提取的浸膏得率和延胡索乙素提取率为考察指标,利用HPLC法测定延胡索乙素的含量。结果:最佳提取工艺为延胡索粉加6倍量80%的乙醉回流提取3次,每次2h。结论:优选得到的工艺简便易行,稳定性好。

关 键 词:延胡索  延胡索乙素  提取工艺  正交试验

Optimization of Extraction Process of Bhizoma Corydalis with Orthogonal Design Method
Abstract:Obijective:To optimize the best extraction process of Rhizoma Corydalis. Method:Using orthogonal design method, to apply extract yield of Rhizoma Corydalis and the extract amount of Trahydropalmetine as ob- serving indexes, to measure the content of Trahydropalmetine with HPLC.Result:The optimum extraction process was as follows, adding 6 times of 80% alcohol into Corydalis meal, refluxing and extraction for 3 times, two hours every time. Conclusion: This optimized process is simple, stable and efficient.
Keywords:Rhizoma Corydalis  Trahydropalmetina  Extraction process  Orthogonal design
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