奥美拉唑治疗急性农药中毒并上消化道出血的效果观察

目的：探讨奥美拉唑治疗急性农药中毒并上消化道出血的临床疗效。方法将2008年2月-2012年12月间我院100例急性农药中毒并上消化道出血患者随机将其分成两组各50例，对照组采用西咪替丁治疗，观察组采用奥美拉唑治疗，每隔2h行胃液潜血实验，并记录潜血转阴时间。比较两组疗效。结果观察组胃液潜血转阴时间明显低于对照组（P 〈0.05），治疗有效率明显高于对照组（P 〈0.05）。结论奥美拉唑治疗急性农药中毒并上消化道出血临床疗效显著，能明显减少患者胃液潜血转阴时间，值得临床应用。

The effect of Omeprazole in treatment of acute pesticide poisoning and upper gastrointestinal bleeding

Objective To investigate the effect of Omeprazole in treatment of acute pesticide poisoning and upper gastrointestinal bleeding. Methods During February 2008-December2012 in our hospital, 100 cases of acute pesticide poisoning and upper gastrointestinal bleeding patients were randomly divided into control group and observation groups, the control group of patients were treated with cimetidine treatment, the observation group were treated with omeprazole therapy, every two hours for juice extraction in patients with gastric occult blood test, and record patient occult blood clearance time. Patient outcomes were compared. Results The gastric occult blood clearance time of the observe group of patients was significantly lower than the control group patients（P 〈0.05）; the effective of the observation group was significantly higher than the efficiency of the control group of patients（P 〈0.05）. Conclusion Omeprazole treatment of acute pesticide poisoning and upper gastrointestinal bleeding significant clinical effect, can significantly reduce patients＇ gastric occult blood clearance time, it was worthy of clinical application.