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结肠癌根治术后复发的多因素分析
引用本文:张军,王越,葛春林.结肠癌根治术后复发的多因素分析[J].中国科学美容,2011(11):12-13,15.
作者姓名:张军  王越  葛春林
作者单位:[1]辽宁中医药大学附属四院肿瘤科,辽宁沈阳110101 [2]中国医科大学附属第一医院肝胆外科,辽宁沈阳110001
摘    要:目的探讨结肠癌根治术后复发的因素。方法对2000年1月~2005年1月收治的135例结肠癌患者的临床资料进行回顾性分析。选择对结肠癌术后复发可能产生影响的临床因素,通过Cox比例风险模型进行多因素分析。结果全组患者复发率为16.3%。单因素分析显示,淋巴结转移、肿瘤大小、Dukes’分期和肿瘤细胞分化程度与结肠癌根治术后肿瘤复发有关。多因素分析显示,淋巴结转移和肿瘤细胞分化程度与结肠癌根治术后肿瘤复发有关。结论淋巴结转移和肿瘤细胞分化程度是影响结肠癌术后复发的独立危险因素。

关 键 词:结肠肿瘤  肿瘤复发  生存分析

Colon Cancer Recurrence after Radical Resection of Multiple Factors
ZHANG dun WANG Yue,GE Chunlin.Colon Cancer Recurrence after Radical Resection of Multiple Factors[J].China Scientific Cosmetology,2011(11):12-13,15.
Authors:ZHANG dun WANG Yue  GE Chunlin
Institution:1.Department of General Surgery, The Forth Affilliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110101 China; 2.Department of Hepatobiliary Surgery, the First Hospital of China Medical University, Shenyang 110001, China)
Abstract:Objective To determine the independent prognostic factors influencing long-term survival rate of the patients with colon cancer after curative resection. Methods Univariate and Cox multivariate regression analysis was performed on 135 patients treated with radical resection from Jan. 2000 to Jan. 2005. Results The overall recurrence was 16.3%. Univariate analysis showed that lymph node involvement, tumor size, Dukes' stage and histological differentiation were correlated to recurrence of colon cancer after operation ; Multivariate analysis showed that lymph node involvement and histological differentiation were significant factors for recurrence rate of colon cancer. Conclusion Lymph node involvement and histological differentiation are independent prognostic factors for colon cancer after radical resection.
Keywords:Colon neoplasms  Neoplasm recurrence  Multivariate regression analysis
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