| 环孢素A治疗儿童难治性肾病综合征26例疗效分析 |
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| 引用本文： | 虞萍,邱建民,陈日雄,李鉴州.环孢素A治疗儿童难治性肾病综合征26例疗效分析[J].中国科学美容,2011(14):12-13. |
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| 作者姓名： | 虞萍 邱建民 陈日雄 李鉴州 |
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| 作者单位： | 广东省从化市中心医院儿科,广东从化510900 |
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| 基金项目： | 广东省医学科学技术研究基金面上项目（编号：WSTJJ20091215） |
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| 摘 要： | 目的探讨环孢素A治疗儿童难治性肾病综合征的临床疗效。方法 26例难治性肾病综合征患儿入院后口服环孢素A,剂量为2～4mg（/kg·d）,同时联合激素治疗,疗程3个月。治疗前及治疗后检测24h尿蛋白定量、血浆白蛋白、血浆胆固醇、尿素氮、血肌酐等指标。结果 26例患儿经治疗后,完全缓解14例,占53.85%;部分缓解10例,占38.46%;未缓解2例,占7.69%。结论环孢素A联合激素能有效治疗难治性肾病综合征。
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| 关 键 词： | 环孢素A 肾病综合征 激素 儿童 |
Clinical effect of cyclosporine A on 26 children in refractory nephrotic syndrome |
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| Institution: | YU Ping ,QIU Jianmin, CHEN Rixiong L,I Jianzhou (Department of Paediatrics,Conghua City Central Hospital of Guangdong Province,Conghua 510900,China) |
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| Abstract: | Objective To explore the clinical curative effect of cyclosporine A to treat children in refractory nephrotic syndrome.Methods The 26 refractory nephrotic syndrome children were treated with CsA,2～4 mg/（kg·d）,Po,and combination with hormone therapy.The course of treatment was 3 months.The 24 h quantitative urinary proteins,plasma albumin,plasma cholesterol,urea nitrogen,plasma creatinine were detected before and after treatment.Results 14 patients（53.84%）were complete,10 patients（38.46%） were part remission,2 cases（7.69%）were non-remission.Conclusion Cyclosporine A combination with hormone to treat children refractory nephrotic syndrome has a significant curative effect. |
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| Keywords: | Cyclosporine A Nephrotic syndrome Hormone Children |
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