| 不同神经保护剂治疗急性脑梗死的疗效比较 |
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| 引用本文： | 付翠萍.不同神经保护剂治疗急性脑梗死的疗效比较[J].中国现代医生,2013(33):79-80,83. |
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| 作者姓名： | 付翠萍 |
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| 作者单位： | 新疆生产建设兵团第五师八十七团医院药剂科,新疆博乐834400 |
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| 摘 要： | 目的探讨不同神经保护剂治疗急性脑梗死的疗效比较。方法选择脑梗死患者80例为研究对象，患者根据使用神经保护剂的不同分为治疗1组、治疗2组和治疗3组各20例，另20例不用神经保护剂，设为对照组。治疗1组采用单唾液酸四己糖神经节苷脂钠治疗，治疗2组采用醒脑静治疗，治疗3组采用奥拉西坦治疗。对照组不使用神经保护剂治疗。评价治疗前后各组患者的NIHSS评分、疗效指数、Barthel指数等。结果治疗后治疗组患者的NIHSS评分和Barthel指数与对照组比较，差异显著（P〈0．05）。结论神经保护剂能够减轻脑卒中后出现的氧化应激和炎症反应，促进神经的再生和修复。
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| 关 键 词： | 神经保护剂 脑梗死 醒脑静 奥拉西坦 |
Clinical effect of different neuroprotective agents for acute cerebral in- farction |
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| Authors: | FU Cuiping |
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| Institution: | FU Cuiping( Department of Pharmacy, Xinjiang Production and Construction Corps, Agriculture Fifth Division, 87 Regiment Hospi- tal, Bole 834400, China) |
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| Abstract: | Objective To discuss clinical efficacy of different neuroprotective agents for acute cerebral infarction. Methods All of 80 cases with acute cerebral infarction were divided into treatment group one, treatment group two, treatment group three, and control group, each of 20 cases. Treatment group one was treated by monosialotetrahexosyl ganglioside sodium. Treatment group two was treated by Xingnaojing. Treatment group three was treated by oxiracetam. Control group treatment by normal therapy. NIHSS, clinical efficacy, Barthel were compared. Results NIHSS score and Barthel index of three treatment groups were better than control group after treatment （P〈0.05）. Conclusion Neuropro- tective agents shows to relieve oxidative stress and inflammatory reaction after acute cerebral infarction, and promote nerves regeneration and restoration. |
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| Keywords: | Neuroprotective agents Cerebral infarction Xingnaojing Oxiracetam |
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