昂丹司琼联合地塞米松在宫颈癌患者术后镇痛中应用效果观察

目的探究昂丹司琼联合地塞米松预防宫颈癌患者手术后镇痛引起的恶心呕吐效果。方法随机将我院2009年1月～2012年12月收治的80例宫颈癌患者分为四组。实验组采取昂丹司琼联合地塞米松．对照组1采用昂丹司琼单独防治，对照组2采用地塞米松单独防治，对照组3设为完全对照组。比较四组患者恶心呕吐情况和术后镇痛效果。结果四组患者VAS评分差异无显著性（P〉0．05），同一组患者不同时间比较，差异无显著性（P〉0．05）。实验组患者恶心呕吐发生率均明显低于对照组；对照组1和对照组2患者则明显低于对照组3，差异均有统计学意义（P〈0．05）。结论昂丹司琼联合地塞米松预防宫颈癌术后镇痛引起恶心呕吐效果理想，优于单用昂丹司琼和地塞米松。

Clinical effects on cervical cancer patients with postoperative analgesia by ondansetron and dexamethasone

Objective To explore and analyze the clinical effects onausea and vomiting caused by postoperative anal- gesia of cervical cancer by ondansetron and dexamethasone. Methods Eighty cases of the cervical cancer patients who were treated in our hospital from January 2009 to December 2012 were divided into four groups randomly. The experi- mental group was prevention and treatment for postoperative nausea and vomiting after operation by ondansetron and dexamethasone while the control group 1 was prevention and treatment for postoperative nausea and vomiting after op- eration by ondansetron alone, the control group 2 was prevention and treatment for postoperative nausea and vomiting after operation by dexamethasone alone. The control group 3 was set as the complete control group. The VAS scores of postoperative analgesia, nnausea and vomiting of the 4 groups were contrasted. Results T.here were no differences among four groups in the VAS scores of postoperative analgesia （P〉0.05）. There were no differences in the same group in the VAS scores of postoperative analgesia among different time （P〉0.05）. The incidence of nausea and vomit- ing caused by radical analgesia after operations of cervical cancer in the experiment group was obviously lower than the control group. The incidence of control group 1 and control group of 2 were lower than the control group 3 （P〈 0.05）. Conclusion The ondansetron and dexamethasone has ideal effects on preventing cervical cancer operation. It is superior to ondansetron and dexamethasone.