米索前列醇联合益母草针剂预防剖宫产术后出血的疗效观察

目的分析米索前列醇联合益母草针剂预防剖宫产术后出血的疗效。方法将2013年1～6月期间来我院住院行剖宫产产妇80例设立为研究对象，随机分为观察组和对照组，各40例，两组均采取相同的剖宫产方式及麻醉方法。对照组于胎儿娩出后宫体注射缩宫素20U、子宫下段注射缩宫素20U，同时口服米索前列醇片200μg。观察组于胎儿娩出后宫体注射缩宫素20U、子宫下段注射益母草针剂2mL，同时口服米索前列醇片200斗g，比较两组产妇的术中出血量、术后2h、12h及24h出血量、产前到产后24h血红蛋白变化情况，并密切观察记录治疗中的不良反应。结果观察组的产妇的术中出血量、产后2h出血量、产后12h出血量、产后24h出血量均分别少于对照组，两组间比较存在极其显著性差异（P〈0．01）。观察组和对照组产前Hb量组间比较，差异无统计学意义（P〉0．05）。产后24h对观察组和对照组的Hb量进行观察，结果显示，观察组和对照组的Hb量均分别较产前减少，且对照组产后24hHb量较观察组降低，但两组间比较差异无显著性（P〉0．05）。结论米索前列醇联合益母草针剂预防剖宫产术后出血疗效确切，无明显不良反应，值得推广和应用。

Efficacy of misoprostol combined with Yimucao for preventiny postopera- tive bleeding of cesarean section

Objective To analyze the effect of misoprostol combined Yimucao prevention after cesarean section hem- orrhage. Methods From January to June 2013 in our hospital ,80 cases of cesarean deliveries in the establishment for the study were randomly divided into observation group and control group 40 cases, both groups took the same ce- sarean production methods and anesthesia. The control group after the baby was delivered at the uterus injected oxy- tocin 20 U, and at the lower uterine segment injected oxytocin 20 U and oral miscoprostol 200 btg. Observation group were injected oxytocin 20 U at the uterus, and Yimucao 2 mL, and oral miscoprostol 200μg, maternal blood loss, post- operative 2 h, 12 h and 24 h the amount of bleeding, prenatal to postnatal 24 h hemoglobin changes were compared, and closely observed and recorded the adverse reactions. Results The observation group of maternal blood loss, 2 h postpartum hemorrhage, postpartum hemorrhage 12 h, 24 h postpartum hemorrhage volume than the control group, respectively,between the two groups there was very significant difference （P 〈 0.01 ）. Observation group and control group ~s antenatal Hb volume between the two groups of the difference was not statistically significant （P 〉 0.05）. Postpartum 24 h, Hb amount of observation group and control group compared with prenatal decreased and the observation group＇s postpartum 24 h Hb decreased compared with the control group, but the difference between the two groups was not significant （P 〉 0.05）. Conclusion Misoprostol combined with Yimucao for bleeding after cesarean section prevention efficacy, no significant adverse reactions, worthy of promotion and application.