左右半结肠癌的差异及临床治疗理念

结肠癌是常见的消化道恶性肿瘤之一，近年来左右半结肠癌治疗和预后的关系愈发受到临床重视。左、右半结肠癌在胚胎来源、解剖结构、生理功能、分子特征、致癌机制、临床特征、治疗疗效、复发转移模式、生存预后方面均存在差异，被认为是完全不同的疾病。在临床治疗和今后的研究中需充分考虑这些特点，才能使治疗更加个体化，研究更具有针对性。

Comparison and treatment of left-and right-side colon cancer

Colorectal cancer is one of the most common malignancies. Various studies have focused on differences between colon can-cers on the left and right sides. These types of colon cancer differ in terms of their molecular features, embryologic origin, anatomy, pathogenesis to physiological functions, clinical features, treatment response, and prognosis. Therefore, the left-and right-side colon cancers are regarded as different diseases. These differences have significant effect on clinical decision-making and personalized medi-cine.