264例乳腺肿块微小切片组织学诊断分析

目的探讨经皮细针乳腺肿块微小碎片组织学（简称微小切片）的诊断价值。方法回顾分析有组织学对比的264例乳腺肿块微小切片与涂片细胞学（简称涂片）检查结果。结果①微小切片对恶性肿瘤诊断敏感性88．1％，良性肿瘤诊断特异性100％，总准确率89．8％；涂片分别为82．7％、93．2％和84、5％；涂片结合微小切片分别为91．6％、93．8％和92．0％。②微小切片与涂片对恶性肿瘤组织分型诊断的准确率分别92．9％、67．6％，2组差异有统计学意义（P〈0．01）；对良性病变的组织分类诊断准确率分别为86．7％和63．6％，P〈0．05。结论微小切片和涂片的诊断准确性均高，两者结合提高诊断准确性；微小切片对恶性肿瘤组织学分型、良性病变分类诊断价值高。

Histological Diagnosis by Fractional Fragment in 264 Cases of Breast Masses

Objective To discuss the histological diagnose value of fractional fragment （FF） got through skin fine needle for breast masses. Methods The diagnosis results of FF and fine needle aspiration cytology （FNAC） in 264 cases with breast masses were analyzed retrospectively. Results （1） To FF,the diagnose sensibility in malignant tumor,diagnose pecuharity in benign lesion and total accurate rate was 88.1%, 100% and 89.8% respectively, and to FNAC was 82.7% ,93.2% and 84.5% respectively. To FNAC plus FF was 91.6% ,93.8% and 92.0% respectively. @） The accurate rate of FF and FNAC for type diagnose in malignant tumor was 92.9% and 67.6% respectively with significant difference（ P 〈0.01 ） ,and in benign lesion was 86.7% and 63.6% respectively with significant difference （P 〈 0.05）. Conclusions Both FF and FNAC have a high accurate in the diagnosis of breast tumor and the combine of the two method can improve the accuracy of diagnosis. FF is very valuable in type diagnose of malignant tumor and classify diagnose of benign lesion