武汉市某社区成年人群慢性肾脏病流行病学调查

目的探讨武汉市江夏区金口街成年人群慢性肾脏病患病情况及相关危险因素。方法采用多阶段整群随机抽样法对该地区1850名20岁以上常住居民进行问卷调查并检测肾脏损伤指标及相关危险因素，包括尿常规、尿白蛋白／肌酐比值、血清生化指标、血红蛋白及肾脏B超等。结果在1850例资料完整的居民中，镜下血尿为5．9％，白蛋白尿检出率为10．3％，肾功能下降为4．2％。该人群中慢性肾脏病患病率12．6％，知晓率6．4％。多因素Logistic回归分析提示，慢性肾脏病的最危险因素为高血压，其余依次为肾结石、高尿酸血症、糖尿病等。结论该区慢性肾脏病患病率较高，慢性肾脏病的疾病谱和相关因素已经与我国大城市和发达国家类似。

Epidemiology of chronic kidney disease among adults in a community of Wuhan city

Objective To study the prevalence of chronic kidney disease（CKD） and risk factors among adults in Jiangxia district Jinkou street of Wuhan city. Methods 1 850 residents（older than 20 years） from Jinkou street of Jiangxia district of Wuhan city were collected using multistage random cluster sampling. All residents were interviewed and given physical examination, and also tested for sample of urine and blood, including urine routine test, urinary albumin to creatinine ratio, serum cre- atinine, blood urea nitrogen, serum uric acid, blood glucose, cholesterol, triglyceride, hemoglobin, kid- ney B-mode ultrasonic examination, etc. Results Eligible data of 1 850 subjects were enrolled in the study. Albuminuria was detected in 10. 3 % of subjects, reduced renal function in 4. 2 %, and microscop- ic hematuria in 5.9%. Approximately 12. 6% of these subjects had at least one indicator of kidney damage. The awareness rate of CKD was 6. 4%. The logistic regression model showed that the strongest risk factor contributed to the development of CKD was hypertension, followed by nephrolithiasis, hyperuricemia,diabetes,central obesity etc. Conclusions The prevalence of CKD in Jinkou district is high. Disease spectrum and related factors of CKD have been similar to our country＇s big cities and the developed coutries.