Antibacterial and antitumor macrolides fromstreptomyces sp. Is9131 |
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| Authors: | Pei -Ji Zhao Li -Ming Fan Guo -Hong Li Na Zhu Yue -Mao Shen |
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| Affiliation: | The State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650204, China. |
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| Abstract: | Four compounds, including two novel macrolides, were isolated from an endophyte Streptomyces sp. Is9131 of Maytenus hookeri. Spectral data indicated that these compounds were dimeric dinactin (1), dimeric nonactin (2), cyclo-homononactic acid (3), and cyclo-nonactic acid (4). Bioassay results showed that dimeric dinactin had strong antineoplastic activity and antibacterial activity. |
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| Keywords: | Macrolide Streptomyces sp. Is9131 Antineoplastic activity Antibacterial activity |
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