Interrelations between macroorganisms and bacteria in wounds and tissues of humans and animals

It is shown that bacteria from the gastrointestinal tract penetrate systematically into the tissues of the focus of damage in man and animals in the blood and lymph. It was found that certain bacterial species maintain vitality in tissues, in which they do not induce pathological reactions but may produce a therapeutic effect due to the production of antibiotics, proteolytic enzymes, immunomodulators, etc. The author describes the results of experimental and clinical study of Sporobacterin, a new agent, intended for the prevention and treatment of surgical infection.