两种不同临床类型的肾黏液性小管状和梭形细胞癌

目的:探讨两种不同临床类型肾黏液性小管状和梭形细胞癌的临床特点。方法:报告2例不同临床类型肾黏液性小管状和梭形细胞癌患者的临床资料,进行对比分析,并复习有关文献。结果:例1为体检发现,无局部及远处转移,无病理性核分裂像,异型性小。例2以持续高热就诊,有局部及远处转移,病理性核分裂像常见,异型性明显。2例均行肾癌根治术,例1术后随访未见复发。例2患者于术后3个月死亡,此为国内首例报道因肾黏液性小管状和梭形细胞癌死亡者。结论:肾黏液性小管状和梭形细胞癌有两种不同临床类型,多数为低度恶性,亦存在恶性程度较高的病例,需区别对待。

Analysis of two kinds of renal mucinous tubular and spindle cell carcinoma

Objective:To investigate the clinical and pathologic feature of two kinds of renal mucinous tubular and spindle cell carcinoma(MTSCC). Method:The clinical date of 2 case of renal MTSCC was reported,the clinical and pathologic feature was analyzed and discussed with literature reviewed. Result:The first patient was incidentally discovered by health examination,with lower nuclear grade,no part and distant metastasis.The second patient presented with persistence hyperpyrexia,part and distant metastasis,and high nuclear grade.Surgery were both performed successfully.The first patient had no recurrences and no distant metastases.The second patient died of multiple organ failure 3 months post operation,it was also the first report of a patient dying of MTSCC in china. Conclusion:Although MTSC is usually a low-grade carcinoma,high grade may occur and lead to a fatal course.So it needs a proper management and prognostication.