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196例药疹住院病例分析
引用本文:闻卫兢,刘玲玲,窦侠,杨建峰,边鹊桥,朱学骏. 196例药疹住院病例分析[J]. 药物不良反应杂志, 2005, 7(4): 259-262
作者姓名:闻卫兢  刘玲玲  窦侠  杨建峰  边鹊桥  朱学骏
作者单位:1. 北京大学第一医院,北京,100034
2. 郑州铁路分局医院,河南,郑州,450053
3. 天津市第三中心医院,天津,300170
摘    要:目的:分析皮科药疹致病药物及临床表现。方法:收集1998-2003年间在我科治疗的196例药疹病历,进行回顾性分析。结果:主要的致病药物依次为抗生素类(96例次),解热镇痛类(27例次),中药类(18例次),磺胺类(17例次),以阿莫西林致病最常见。皮疹类型以发疹型(105例次)为主。结论:抗生素类药物引起药疹比较常见,中药引起药疹的发病率有上升的趋势,在临床工作中应引起重视。

关 键 词:药疹  抗生素  阿莫西林
文章编号:1008-5734(2005)4-0259-04

Analysis of 196 inpatients with drug eruption
Wen Weijing,Liu Lingling,Dou Xia,Yang Jianfeng,Bian Queqiao,Zhu Xuejun. Analysis of 196 inpatients with drug eruption[J]. Adverse Drug Reactions Journal, 2005, 7(4): 259-262
Authors:Wen Weijing  Liu Lingling  Dou Xia  Yang Jianfeng  Bian Queqiao  Zhu Xuejun
Abstract:Objective: To analyse the causative agents and the clinical features of drug eruption. Methods: The clinical data of 196 patients hospitalized for drug eruption in dermatology department from 1998 to 2003 were retrospectively analyzed. Results: The main causative agents were with antibiotics (96 case-times), followed by analgesics-antipyretics(27), traditional Chinese medicines(18)and sulfonamides(17).The most common causative drug was amoxycillin, and the most common form of drug eruption was exanthematous one. Conclusion: Antibiotics-induced eruption is common, and traditional Chinese medicine-induced eruption is increasing, so caution is need when using these products.
Keywords:drug eruption  antibiotics  amoxycillin
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