运动对大鼠额叶和纹状体一氧化氮合酶阳性细胞的影响

目的　研究运动对运动中枢神经型一氧化氮合酶阳性细胞的影响。方法　将大鼠分为对照组和运动组 ,运动组大鼠游泳 5d ,用免疫组织化学方法检测额叶、纹状体一氧化氮合酶阳性细胞的变化。结果　运动组额叶、纹状体一氧化氮合酶阳性细胞的染色比对照组深 ,运动组额叶阳性细胞数量平均每张切片为 (7.2± 1.9)个 ,比对照组 (2 .4± 0 .6 )个明显增加 (P <0 .0 5 ) ,运动组纹状体阳性细胞数量平均每张切片为 (35 .0± 7.2 )个 ,也比对照组 (8.2± 1.3)个增加显著 (P <0 .0 1)。结论　运动增加了运动中枢一氧化氮合酶阳性细胞的表达

Effect of exercise on nitric oxide synthase-positive neurons of the frontal lobe and striatal body in rat

Objective To study the effect of exercise on nitric oxide synthase(Nos) positive neurons of the exercise center in the brain.Methods Rats were divided into two groups: the control group and the exercise group. The rat in the exercise group swimmed five days. The change of the Nos positive neurons of the frontal lobe and striatal body were studied in immuohistochemical method.Results The staining of the Nos positive neurons of the frontal lobe and striatal body in the exercise group were stronger than in the control group. The number of the Nos positive neurons of the frontal lobe which were 7.2±1.9 per section in the exercise group were higher than the control group which were 2.4±0.6 per section (P<0.05), while the number in the striatal body which were 35.0±7.2 per section were higher than the control group which were 8.2±1.3 per section (P<0.01). Conclusion Exercise increased the expression of the Nos positive neurons of the exercise center in the brain.