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| 噪声作业工人血浆热应激蛋白60抗体与高血压的关系研究 | |
| 引用本文： | 姚惠琳,李毅,杨杪,陈胜,郑建如,杨秋玲,邬堂春.噪声作业工人血浆热应激蛋白60抗体与高血压的关系研究[J].中国全科医学,2006,9(21):1758-1760. |
| 作者姓名： | 姚惠琳 李毅 杨杪 陈胜 郑建如 杨秋玲 邬堂春 |
| 作者单位： | 1. 442000,湖北省十堰市东风职业病防治所 2. 郧阳医学院附属东风医院检验部 3. 华中科技大学同济医学院公共卫生学院 |
| 基金项目： | 国家自然科学基金;湖北省科技攻关项目 |
| 摘 要： | 目的探讨噪声作业工人血浆热应激蛋白（HSP）60抗体与高血压之间的关系。方法用Western blot免疫印迹法测定噪声作业工人血浆HSP60抗体水平。用多因素Logistic回归模型分析HSP60抗体水平与高血压的关系。结果高血压组调查对象HSP60抗体阳性率为13．86％，血压正常组为6.55％，差别有显著性意义（P〈0．05）；在排除了常见高血压病危险因素的影响后，高血压与HSP60抗体之间仍然存在着较强联系（P〈0．05）。结论血浆HSP60抗体可能是噪声作业工人高血压的危险因素。 |
| 关 键 词： | 噪声 热应激蛋白60抗体 高血压 |
| 文章编号： | 1007-9572（2006）21-1758-03 |
| 收稿时间： | 2006-08-12 |
| 修稿时间： | 2006年8月12日 |
Study on Relationship between Antibody against Heat Stress Protein 60 and Hypertension in Workers Exposed to Noise |
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| YAO Hui - lin, LI Yi, YANG Miao,et al..Study on Relationship between Antibody against Heat Stress Protein 60 and Hypertension in Workers Exposed to Noise[J].Chinese General Practice,2006,9(21):1758-1760. | |
| Authors: | YAO Hui - lin LI Yi YANG Miao |
| Institution: | YAO Hui - lin, LI Yi, YANG Miao, et al. |
| Abstract: | Objective To explore the relationship between antibody against heat stress protein 60 (HSP 60) and hypertension in the workers exposed to noise.Methods Serum anti-HSP 60 was determined with Western blotting technique in the workers exposed to noise.Logistic regression model was used to analyze the relationship between anti-HSP 60 and hypertension.Results The positive rate of anti-HSP 60 in the hypertension group was 13.86%,significantly higher than 6.55% in the control group.After adjusted by the generally recognized risk factors for hypertension,there was still a strong association between anti-HSP 60 and hypertension.Conclusion Anti-HSP 60 may be a risk factor of hypertension in the workers exposed to noise. |
| Keywords: | Noise Antibodies against heat stress protein 60 Hypertension |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |