| 固相萃取-气相色谱-质谱联用法测定白术中8种有机氯农药的残留量 |
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| 引用本文： | 翟枫,金立弟,戴博,周敏.固相萃取-气相色谱-质谱联用法测定白术中8种有机氯农药的残留量[J].中国医院用药评价与分析,2013(10):914-917. |
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| 作者姓名： | 翟枫 金立弟 戴博 周敏 |
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| 作者单位： | [1]吉林市食品药品检验所,吉林吉林132000 [2]空军总医院药学部,北京100142 |
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| 摘 要： | 目的：建立固相萃取-气相色谱-质谱联用法同时测定白术中8种有机氯农药残留量。方法：样品以丙酮超声提取,采用氨基固相萃取柱进行净化,气相色谱-质谱联用技术进行测定。结果：8种有机氯农药在10~1 000μg/L范围内呈良好的线性关系,8种农药的检测限在0.3~2.0μg/kg之间,定量限在1.0~6.0μg/kg之间,3个水平添加回收率在82.07%~105.13%之间,相对标准偏差（RSD）〈6%（n=9）。结论：本方法灵敏度高,重现性好,可用于白术中8种有机氯农药残留量的检测。
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| 关 键 词： | 氨基固相萃取 气相色谱-质谱 白术 有机氯农药 |
Determination of 80rganochlorine Pesticides in Atractylodes Macrocephala by SPE-GCMS |
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| ZHAI Feng,JIN Li-diI,DAI Bo,ZHOU Min.Determination of 80rganochlorine Pesticides in Atractylodes Macrocephala by SPE-GCMS[J].Evaluation and Analysis of Drug-Use in Hospital of China,2013(10):914-917. |
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| Authors: | ZHAI Feng JIN Li-diI DAI Bo ZHOU Min |
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| Institution: | 1. Jilin Institute for Food and Drug Control, Jilin Jilin 132000, China; 2. Dept. of Pharmacy, Air Force General Hospital, Beijing 100142, China) |
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| Abstract: | OBJECTIVE：To establish an SPE-GC-MS （Solid Phase Extraction-Gas Chromatography-Mass Spectrometry） method for the simultaneously determination of 8 organoehlorine pesticides in Atractylodes Macrocephala. METHODS： The sample was extracted ultrasonically using acetone, purified using NH2-solid phase extraction column and determined by GC-MS. RESULTS： The linear range of the 8 organochlorine pesticides was 10-1 000 μg/L, and their limits of detection （LOD） ranged within 0. 3-2. 0μg/kg and limits of quantitation （LOQ） ranged at 1.0-6.0μg/kg. The average fortified recovery rates at three levels ranged at 82.07%-105.13% with relative standard deviations （RSD） less than 6% （n = 9 ）. CONCLUSION： The method is sensitive and reproducible and it can be used for the detection of pesticide residues of 8 organochlorine in Atractylodes Macrocephala. |
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| Keywords: | NH2-SPE GC-MS Atractylodes Macrocephala Organochlorine pesticides |
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