上海市某区17家医院集中采购抗菌药物情况分析

目的：了解上海市某区抗菌药物应用的现状及用药特点，为临床合理用药提供依据、方法：采用购药金额排序法、用药频度（DDDs、排序法，统计上海市某区17家医院2012年抗菌药物集中采购情况，对购药领先的品种进行分析。结果：2012年抗菌药物购药金额占全部药物总购药金额的8．37％（8720．13／104185．67万元），其中头孢菌素类购药金额约占抗菌药物购药金额的1／2；抗菌药物共涉及131个品规，其中头孢菌素类有46个，占35．11％。DDDs排序前3位抗菌药物种类依次是头孢菌素类、氟喹诺酮类和大环内酯粪，其DDC分别为16．2、7．69和14．14元。结论：充分掌握《抗菌药物临床应用指导原则》，不断总结与了解细菌感染的临床流行病学特点，尽量做到循证应用，制定适合的给药方案，合理使用抗菌药物。

Analysis of Centralized Purchase of Antibiotics in 17 Hospitals of Shanghai

OBJECTIVE：To investigate the status quo and the characteristics of the application of antibiotics in a district of Shanghai so as to provide references for clinical rational use of drugs. METHODS： The data of centralized purchase of antibiotics in 17 hospitals of Shanghai during 2012 and the leading varieties of antibiotics purchased were analyzed statistically by ranking method of purchase sum （of money） and DDDs. RESULTS： During 2012, the purchase sum of antibiotics representing 8.37% of total （8 720. 13/104 185.67 unit： 10 000 Yuan）, wilh cephalosporins accounting for about half of the total antibiotics in terms of purchase sum. The antibiotics totaled 131 categories, of which, 46 were cephalosporins, accounting for 35%. Cephalosporins, quinolones and macrolides dominated the top three places on the list of DDDs, with their DDC at 16.2 yuan, 7.69 yuan and 14. 14 yuan, respectively. CONCLUSION ： It is important to fully understand the ＂Guiding Principles on Clinical Use of Antibiotics＂, constantly sum up and familiarize the clinical epidemiological characteristics of bacterial infection, try to make evidence-based applications, develop appropriate dosing regimen to achieve rational use of antibiotics.