南京医科大学附属南京妇幼保健院I类切口手术围术期抗菌药物应用分析

目的：了解我院I类切口手术围术期预防性应用抗菌药物情况，为加强抗菌药物的合理使用和规范化管理提供参考。方法：对我院2013年4月抽取的I类切口手术患者围术期预防性应用抗菌药物情况进行回顾性统计分析。结果：抗菌药物使用率为23．16％；术前预防性给药时间≤2h的有3例（占13．64％），〉2h的有7例（占31．82％）；用药疗程≤24h的有4例（占18．18％）、≤48h的有7例（占31．82％）、≤72h的有1例（占4．55％），〉72h的有10例（占45．45％）。抗菌药物使用率最高的是硝基咪唑类。结论：我院I类切口手术预防性应用抗菌药物还存在不舍理之处，应加强围术期抗菌药物使用的培训和监管，促进临床合理用药。

Analysis of Perioperative Use of Prophylactic Antibiotics in Patients Undergoing Type I Incision Operation in Nanjing Maternity and Child Health Hospital Affiliated to Nanjing Medical University

OBJECTIVE ： To investigate the perioperative use of prophylactic antibiotics in patients undergoing type I incision operation in our hospital so as to provide reference for rational use and standardized management of antibiotics. METHODS： By a retrospective study, the perioperative use of prophylactic antibiotics for the sampled patients undergoing type I incision operation in our hospital in April of 2013 was analyzed statistically. RESULTS ： The rate of antibiotic use was 23.16%. Preoperatively, antibiotics were used at ≤2 h in 3 eases （ 13.64% ） and at 〉 2h in 7 cases （31.82%）. Antibiotics were administered for duration of ≤24 h in 4 cases （ 18.18% ）, for ≤48 h in 7 cases （31.82%）, for ≤72 h （4.55%） in 1 case （4.55%） and for 〉72 h in 10 cases （45.45%）. Nitroimidazoles were the antibiotic type that used most frequently among all the antibiotics used. CONCLUSION： The perioperative use of prophylactic antibiotics in patients undergoing type I incision operation in our hospital was irrational to some extent; therefore, it is urgent to intensify training and supervision on perioperative use of antibiotics so as to promote clinical rational use of drugs.