ω-3脂肪酸对胃癌新辅助化疗患者术后康复中的作用研究 |
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引用本文: | 张斌,姬社青,陈小兵,王修身,金歌,罗素霞,花亚伟,刘英强.ω-3脂肪酸对胃癌新辅助化疗患者术后康复中的作用研究[J].中国当代医药,2011,18(25):13-15. |
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作者姓名: | 张斌 姬社青 陈小兵 王修身 金歌 罗素霞 花亚伟 刘英强 |
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作者单位: | 1. 河南省肿瘤医院普通外科,河南,郑州,450007 2. 河南省肿瘤医院肿瘤内科,河南,郑州,450007 3. 河南省肿瘤医院放疗科,河南,郑州,450007 4. 郑州大学第一附属医院心内科,河南,郑州,450052 |
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摘 要: | 目的:观察ω-3脂肪酸在胃癌新辅助化疗患者术后康复中的作用。方法:选择进展期胃癌40例,采用mFOLFOX-6方案术前化疗2周期,对照组(20例)术后常规治疗,治疗组(20例),术前1d及术后6d加用ω-3脂肪酸,观察两组患者手术后康复有无差异。结果:两组患者术后2、4、6dC反应蛋白(CRP)比较,差异具有统计学意义;两组患者手术后2、4、6dSIRS(全身炎症反应综合征)发生率,切口感染、吻合口瘘发生率,及术后静脉导管相关感染、血液感染及肺部感染率比较,差异无统计学意义(P〉0.05)。结论:ω-3脂肪酸能降低患者炎症反应,促进患者康复。
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关 键 词: | 进展期胃癌 新辅助化疗 氟尿嘧啶 奥沙利铂 根治术 ω-3脂肪酸 |
Effect of Fatty Acids Omega-3 to postoperative rehabilitation in gastric cancer undergoing neoadjuvant chemotherapy. |
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Authors: | ZHANG Bin JI Sheqing CHEN Xiaobing WANG Xiushen JIN Ge LUO Suxia HUA Yawei LIU Yingqiang |
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Institution: | 1.General Surgery of Henan Tumor Hospital,Henan Province,Zhengzhou 450007,China;2.Medical Department of Henan Tumor Hospital,Henan Province,Zhengzhou 450007,China;3.Medical Department of the First Affiliated Hospital of Zhengzhou University,Henan Province,Zhengzhou 450052,China;4.Radiotherapy Department of Henan Tumor Hospital,Henan Province,Zhengzhou 450007,China |
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Abstract: | Objective:To evaluate the efficacy of Fatty Acids Omega-3 to postoperative rehabilitation in gastric cancer undergoing neoadjuvant chemotherapy.Methods:Patients with previously untreated advanced gastric cancer received mFOLFOX-6 neoadjuvant chemotherapy;twenty patients received Fatty Acids Omega-3 from one day preoperative to six days of postoperative the patients in the control group received basic treatment.Results:The difference of CRP 2,4,6 day of postoperative between two groups was statistically significant.Conclusion:Fatty Acids Omega-3 can degrade inflammatory reaction and encourage rehabilitation of gastric cancer undergoing neoadjuvant chemotherapy. |
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Keywords: | Gastric cancer Neoadjuvant chemotherapy Fluorouracil Oxaliplatin Radical correction Fatty Acids Omega-3 |
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