Increased adenosine deaminase in hydatidiform mole. |
| |
| Authors: | Yaprak Engin-Ustün Yusuf Ustün Aysun Bay Karabulut Keziban Do?an M Mutlu Meydanli Bülent Sezgin |
| |
| Institution: | Department of Obstetrics and Gynecology, School of Medicine, Inonu University, Malatya, Turkey. ustunyaprak@yahoo.com |
| |
| Abstract: | BACKGROUND: The aim of the current study was to investigate levels of adenosine deaminase in plasma of patients with hydatidiform mole. METHODS: Plasma adenosine deaminase levels were determined in 17 women with normal pregnant course, in 17 women with hydatidiform mole, and in 17 non-pregnant healthy volunteers. RESULTS: Mean adenosine deaminase activity in the hydatidiform mole group was 121.5+/-24.8 U/L, significantly higher than in the pregnant control (7.8+/-6.5 U/L; p<0.0001) and non-pregnant control groups (6.4+/-7.4 U/L; p<0.0001). A cutoff level of 40.5 U/L was found, with both sensitivity and specificity of 100%. CONCLUSIONS: Adenosine deaminase may play a role in the development of hydatidiform mole. |
| |
| Keywords: | |
|
|
