Serum squamous cell carcinoma antigen levels in women with neoplasms of the lower genital tract and in healthy controls |
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Authors: | W Neunteufel G Tatra Ch Bieglmayer |
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Institution: | (1) 2nd Department of Obstetrics and Gynecology, University of Vienna, Vienna, Austria;(2) Department of Obstetrics and Gynecology, Krankenhaus Hollabrunn, Winiwarterstr. 6, A-2020 Hollabrun, Austria |
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Abstract: | Summary Squamous cell carcinoma antigen levels in 74 healthy volunteers, 57 patients with CIN and 91 patients with cervical carcinoma were determined by radioimmunoassay. 5.4% of healthy volunteers were above and all patients with CIN were below 3.0 ng/ml. 63.1% of 65 patients with primary squamous cell carcinoma, 1 out of 7 adenocarcinomas and 68.4% of 19 patients with recurrence of squamous cell carcinoma of the cervix had elevated SCC antigen levels. Elevated posttreatment levels carried a high risk factor of tumor persistence. Increases in SCC antigen levels during follow up usually signified recurrent carcinoma. |
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Keywords: | SCC antigen Cervical carcinoma Vaginal carcinoma Vulvar carcinoma |
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