| 克拉霉素制备中副产物的纯化与结构确证 |
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| 引用本文： | 顾慧儿,许先栋,陶珍,赵淑敏,吴香玫. 克拉霉素制备中副产物的纯化与结构确证[J]. 中国医药工业杂志, 2000, 31(3): 119-121 |
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| 作者姓名： | 顾慧儿 许先栋 陶珍 赵淑敏 吴香玫 |
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| 作者单位： | |
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| 摘 要： | 在以红霉素A为原料制备克拉霉素时,将一个副产物纯化至HPLC检测纯度在98%以上,通过理化性质测定,确证其结构为红霉素烯醇醚。
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| 关 键 词： | 克拉霉素 红霉素 副产物 烯醇醚 结构 |
| 修稿时间： | 1998-08-23 |
Isolation and Structure Elucidation of a Side Product in Clarithromycin Preparation |
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| GU Hui Er,XU Xian Dong,TAO Zhen,ZHAO Shu Min,WU Xiang Mei. Isolation and Structure Elucidation of a Side Product in Clarithromycin Preparation[J]. , 2000, 31(3): 119-121 |
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| Authors: | GU Hui Er XU Xian Dong TAO Zhen ZHAO Shu Min WU Xiang Mei |
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| Abstract: | A side product in preparation of clarithromycin was isolated and its structure was elucidated by UV,IR,NMR and MS spectra as the internal enol ether of erythromycin. |
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| Keywords: | clarithromycin erythromycin side product internal enol ether structure |
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