| 铁炭复合磁性载体的制备及性能测定 |
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| 引用本文： | 曹宏明,黄广建,宣绍峰,李春忠,王淑芬. 铁炭复合磁性载体的制备及性能测定[J]. 医学教育探索, 2007, 0(5): 652-656 |
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| 作者姓名： | 曹宏明 黄广建 宣绍峰 李春忠 王淑芬 |
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| 作者单位： | 华东理工大学超细材料制备与应用教育部重点实验室;复旦大学附属华山医院;华东理工大学国家超细粉末工程研究中心; |
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| 基金项目： | 国家自然科学基金资助项目(30471682);;上海市基础研究重点项目(05JC14016);;国家科技部重大基础研究前期研究专项资助项目(2002CCA01100) |
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| 摘 要： | 采用中和沉淀法对球磨法制备的Fe3O4/C初级复合磁性载体进行了表面改性,并经过固相高温还原得到了铁炭复合磁性载体。制备的载体分别用TEM、XRD、TG及TPM-7 BH仪进行了表征。考察了磁靶向药物载体的热稳定性,并对其在空气中磁性能的变化规律及其在类似人体的环境中磁性能的变化趋势进行了考察。结果表明:所制备的复合磁性载体能满足实际应用的要求。
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| 关 键 词： | 铁炭复合磁性载体 磁靶向 缓释 |
Preparation and Characterization of Iron-Carbon Composite Magnetically Targeted Carriers |
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| CAO Hong-ming,HUANG Guang-jian,XUAN Shao-feng,LI Chun-zhong,WANG Shu-fen. Preparation and Characterization of Iron-Carbon Composite Magnetically Targeted Carriers[J]. Researches in Medical Education, 2007, 0(5): 652-656 |
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| Authors: | CAO Hong-ming HUANG Guang-jian XUAN Shao-feng LI Chun-zhong WANG Shu-fen |
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| Affiliation: | 1;2;1.Key Laboratory for Ultrafine Materials of Ministry of Education;East China University of Science and Technology;Shanghai 200237;China;2.National Engineering Research Center of Ultrafine Powder;3.Huashan Hospital;Fudan University;Shanghai 200400;Chin |
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| Abstract: | Surface modification of the ball-mill prepared Fe_3O_4/C magnetic composites was carried out using a precipitation method.Fe/C magnetic composites were obtained by solid-state high-temperature(deoxidating) of the modified Fe_3O_4/C magnetic composites.The obtained products were characterized by transmission electron micrograph(TEM) images,X-ray diffraction(XRD) pattern,thermogravimetric(analysis)(TG) and grain-size distribution.The thermal stability of the drug targeting magnetic composites and the change o... |
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| Keywords: | iron-carbon magnetic composite magnetic targeting controlled desorption |
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